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Clozapine and associated diabetes mellitus
A P Popli1, P E Konicki, G J Jurjus
1Psychiatry Service, Cleveland Veterans Affairs Medical Center, Case Western Reserve University School of Medicine, Ohio, USA.
The Journal of Clinical Psychiatry
|March 1, 1997
Summary
Clozapine, an antipsychotic, may cause new-onset or worsening diabetes mellitus. Close blood sugar monitoring is crucial for patients with diabetes history during clozapine treatment.
Area of Science:
- Psychiatry
- Endocrinology
Background:
- Clozapine is a vital treatment for refractory psychosis.
- Known adverse effects include sedation, weight gain, and seizures.
- Hematologic changes like agranulocytosis are also associated with clozapine.