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Lactoferrin in tears in contact lens wearers
M J Velasco Cabrera1, J García Sánchez, F J Bermúdez Rodríguez
1Department of Optics, Science Faculty, University of Granada, Spain.
Purpose:
The purpose of this study was to examine the concentration of lactoferrin in 126 healthy subjects before being fitted with contact lenses. We obtained repeat measurements 9 months following contact lens fitting in patients who developed giant papillary conjunctivitis and in those who were successful contact lens wearers.
Methods:
We accomplished tear stimulation by the use of Allyl sulphide, a non-toxic organic compound. We measured lactoferrin by the radial immuno-diffusion technique.
Results:
We found a significant decrease of lactoferrin levels in the tears of patients with giant papillary conjunctivitis.