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Microbiology of recurrent parotitis
M S Giglio1, M Landaeta, M E Pinto
1Department of Microbiology, Faculty of Medicine, University of Chile, Santiago, Chile. drosgros@inet.macland.cl
The Pediatric Infectious Disease Journal
|April 1, 1997
Summary
Infantile chronic recurrent parotitis (ICRP) involves recurrent parotid gland swelling. High concentrations of Streptococcus pneumoniae and Haemophilus influenzae in saliva suggest their role in ICRP development.
Area of Science:
- Microbiology
- Pediatric Medicine
- Otolaryngology
Background:
- Infantile chronic recurrent parotitis (ICRP) presents as recurrent parotid gland swelling, decreased salivary flow, and purulent secretions.
- The exact causes of ICRP remain largely unknown, with suspected factors including anatomical abnormalities, bacterial infections, and immune system disorders.
Purpose of the Study:
- To identify and quantify microorganisms involved in infantile chronic recurrent parotitis (ICRP).
- To assess the antimicrobial susceptibility of isolated pathogens.
Main Methods:
- Saliva samples were collected from 56 ICRP patients and 20 controls.
- Samples were cultured under aerobic and anaerobic conditions, followed by antimicrobial susceptibility testing and serotyping.
Main Results:
- 91% of ICRP patient samples were culture-positive, predominantly for Streptococcus pneumoniae and Haemophilus influenzae.
- 65% of control samples were culture-positive, mainly for viridans streptococci, but with lower colony counts.
- Penicillin resistance was observed in about one-third of S. pneumoniae strains; all H. influenzae strains were susceptible to tested antimicrobials.
Conclusions:
- High concentrations of S. pneumoniae and H. influenzae in ICRP patients, compared to controls, indicate their potential role in the condition.
- Quantitative cultures are crucial for evaluating the pathogenic significance of these bacteria in ICRP.
- Further research into the specific mechanisms of these bacteria in ICRP pathogenesis is warranted.