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Multiplexed DNA sequencing and diagnostics by hybridization with enriched stable isotope labels

H F Arlinghaus1, M N Kwoka, X Q Guo

  • 1Atom Sciences, Inc., Oak Ridge, Tennessee 37830, USA.

Analytical Chemistry
|April 15, 1997
PubMed
Summary

A new DNA sequencing method uses stable isotopes and time-of-flight resonance ionization mass spectrometry (TOF-RIMS) for rapid analysis. This technique enables simultaneous detection of multiple DNA probes, enhancing diagnostic capabilities.

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