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Conjunctival neurilemoma. Report of 3 cases
N C Charles1, D M Fox, J A Avendaño
1Department of Ophthalmology, New York University Medical Center, New York City, USA.
Archives of Ophthalmology (Chicago, Ill. : 1960)
|April 1, 1997
Summary
Conjunctival neurilemoma, a rare eye tumor, was observed in three women. These benign tumors, confirmed by S-100 protein staining, occurred on the bulbar and tarsal conjunctiva without other health issues.
Area of Science:
- Ophthalmology
- Oncology
- Surgical Pathology
Background:
- Neurilemoma, also known as schwannoma, represents a rare tumor arising from nerve sheath cells.
- Ocular involvement by neurilemoma is infrequent, with conjunctival presentation being exceptionally rare.
Observation:
- Three cases of benign conjunctival neurilemoma were identified in adult women.
- Tumors were located on the bulbar conjunctiva (two cases) and tarsal conjunctiva (one case).
- Patients had no concurrent ocular or systemic diseases.
Findings:
- Histopathological examination confirmed the diagnosis of neurilemoma.
- Immunoperoxidase staining demonstrated positivity for S-100 protein in all three tumors, a characteristic marker for neural crest-derived tumors.
- The tumors were surgically excised and confirmed as benign.
Implications:
- This report expands the understanding of rare conjunctival tumors and their clinical presentation.
- Conjunctival neurilemoma should be considered in the differential diagnosis of conjunctival masses.
- S-100 protein positivity is a key diagnostic indicator for conjunctival neurilemoma.
