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[Chorea: clinical analysis of 119 cases]

M F Mendes1, L A de Andrade, H B Ferraz

  • 1Setor de Investigação em Moléstias Extrapiramidais da Disciplina de Neurologia da Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), Brasil.

Arquivos De Neuro-Psiquiatria
|September 1, 1996
PubMed
Summary

Sydenham's chorea (SC) is the most common cause of chorea in Brazil, affecting over 51% of patients. This study highlights the prevalence of SC and other chorea etiologies in a Brazilian movement disorders unit.

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Area of Science:

  • Neurology
  • Movement Disorders
  • Clinical Syndromes

Context:

  • Chorea is a neurological syndrome with diverse global etiologies.
  • Understanding regional variations in chorea causes is crucial for diagnosis and treatment.
  • Brazil presents a unique epidemiological profile for chorea.

Purpose:

  • To investigate the etiological spectrum of chorea in a Brazilian university hospital.
  • To analyze the prevalence of different chorea causes within the studied population.
  • To propose an etiological classification of chorea based on clinical experience and literature review.

Summary:

  • A retrospective study analyzed 119 patients diagnosed with chorea in Brazil.
  • Sydenham's chorea (SC) was the predominant etiology (51.3%), followed by Huntington's chorea (18.5%) and post-stroke chorea (9.2%).

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  • SC, though less common in developed nations, remains prevalent in Brazil, particularly in younger females.

    • Impact:

    • The findings emphasize the significant burden of Sydenham's chorea in Brazil.
    • This study contributes to a better understanding of chorea's diverse etiologies in South America.
    • The proposed etiological classification can aid clinicians in diagnosing and managing chorea patients effectively.