Related Experiment Video
Updated: Aug 9, 2026
A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
Published on: August 14, 2013
A pilot randomized controlled study on the effect of laser photocoagulation of confluent soft macular drusen
H L Little1, J M Showman, B W Brown
1Zweng Memorial Retinal Research Foundation, Menlo Park, California 94025, USA.
Purpose:
The authors determined the effect of photocoagulation of drusen on visual acuity and progression to subretinal neovascular membranes (SRNV).
Methods:
One of paired eyes was randomized to photocoagulation with other eye to control in 27 patients having symmetrical maculopathy and visual acuities, aged 46 to 81 years (mean, 69.7 years); follow-up 1 to 6 years (mean, 3.2 years).
Results:
Final visual acuity was improved in treated eye or decreased in control eye in 12 patients, equal in 13 patients, and decreased in treated eye in 2 patients (P < 0.006). Progression to SRNV was less with treatment.
Conclusion:
Laser photocoagulation of confluent soft macular drusen may improve long-term visual prognosis.
