Related Experiment Videos
Hippocampal atrophy secondary to entorhinal cortical degeneration in Alzheimer-type dementia
1Department of Neuropathology, Tokyo Metropolitan Institute of Gerontology, Japan.
Neuroscience Letters
|January 31, 1997
Abstract:
Pathological comparison between cases with Alzheimer-type dementia (ATD) and the non-demented cases with infarct showed that hippocampal atrophy in ATD could be caused mainly by degeneration of the stratum lacunosum-radiatum rather than neuronal loss in the pyramidal layer of the hippocampus, and that degeneration of the stratum lacunosum-radiatum could be secondary mainly to the entorhinal cortical degeneration.