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Gene Transfection toward Spheroid Cells on Micropatterned Culture Plates for Genetically-modified Cell Transplantation
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Transplantation of cells in an immunoisolation device for gene therapy

V E Carr-Brendel1, R L Geller, T J Thomas

  • 1Gene Therapy Unit, Baxter Healthcare Corp., Round Lake, IL, USA.

Methods in Molecular Biology (Clifton, N.J.)
|January 1, 1997
PubMed
Abstract

No abstract available in PubMed .

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Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...
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