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Gastric adenocarcinoma and low-grade B-cell lymphoma of mucosa-associated lymphoid tissue
W J Hardman1, A A Gal, R R Pascal
1Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Ga 30322, USA.
Southern Medical Journal
|April 1, 1997
Abstract:
We describe the synchronous occurrence of gastric signet-ring cell adenocarcinoma and low-grade B-cell lymphoma of mucosa-associated lymphoid tissue in a patient with chronic gastritis and intestinal metaplasia. Histologic features of the mucosal inflammation, a follicular gastritis, were suggestive of a chronic Helicobacter pylori infection. Previous hypotheses concerning the relationship of long-standing gastritis and development of gastric carcinoma and lymphoma are supported by our findings.