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Related Experiment Videos

Heart rate variability in the dog: is it too variable?

S L Minors1, M R O'Grady

  • 1Department of Clinical Studies, Ontario Veterinary College, University of Guelph.

Canadian Journal of Veterinary Research = Revue Canadienne De Recherche Veterinaire
|April 1, 1997
PubMed
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Resting heart rate variability (HRV) is not a reliable screening tool for early canine dilated cardiomyopathy (DCM). While HRV showed variability, reduced fractal power may indicate early autonomic dysfunction preceding DCM development in Dobermans.

Area of Science:

  • Veterinary Cardiology
  • Autonomic Function Testing
  • Canine Heart Disease

Background:

  • Autonomic dysfunction can precede clinical signs of dilated cardiomyopathy (DCM).
  • Heart rate variability (HRV) is a noninvasive measure of autonomic nervous system activity.
  • Early detection of DCM in Dobermans is crucial for prognosis.

Purpose of the Study:

  • To assess resting HRV as a screening tool for early autonomic derangement in Dobermans.
  • To identify HRV parameters predicting the development of occult DCM within one year.
  • To correlate HRV with plasma catecholamines as markers of sympathoexcitation.

Main Methods:

  • Evaluated time and frequency domain HRV parameters in 32 healthy Doberman pinschers.
  • Monitored dogs for the development of occult DCM over one year.

Related Experiment Videos

  • Correlated HRV parameters with plasma norepinephrine levels.

    • Main Results:

    • Seven of 32 healthy dogs developed occult DCM.
    • No HRV parameters were significantly associated with DCM development via univariate logistic regression.
    • In dogs with occult DCM, plasma norepinephrine inversely correlated with fractal power and other spectral components, suggesting parasympathetic withdrawal.

    Conclusions:

    • Resting HRV is currently inadequate as a screening test for early occult DCM in Dobermans due to high variability.
    • Parasympathetic withdrawal, indicated by reduced fractal power, may be an early sign of DCM development.
    • Further research into specific HRV components may refine its diagnostic utility for early DCM detection.