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[Clinical use of recombinant gonadotropins (FSH, LH, hCG)]
J M Antoine1, E Loumaye, S Alvarez
1Service de Gynécologie-Obstétrique, Hôpital Tenon, Paris.
Abstract:
The production of recombinant gonadotropins is independent of urine collection. They have a high specific activity and a better batch to batch consistency than urinary gonadotropins. In our IVF programme 62 normo-ovulatory patients less than 38 years old, with tubal or idiopathic infertility and normal sperm, were treated by r-FSH and randomized into four groups : with or without LHRH agonist, step-up or step-down stimulation. The overall results were higher in the agonist groups, but did not reveal any significant difference between step-up and step-down stimulation.