Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Primary cardiac angiosarcoma: clinical and pathological diagnostic problems

M N Afzal1, A Alguacil-Garcia

  • 1Department of Pathology, Health Sciences Centre, University of Manitoba, Winnipeg. afzal@cc.umanitoba.ca

The Canadian Journal of Cardiology
|March 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy and tolerability of tegaserod in constipation dominant irritable bowel syndrome.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP·2004
Same author

Atherosclerosis and plaque rupture: an update.

JPMA. The Journal of the Pakistan Medical Association·1999
Same author

Moderately differentiated neuroendocrine carcinoma in the floor of the mouth: a case report.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons·1999
Same author

Sudden death after a cold drink: case report.

The American journal of forensic medicine and pathology·1999
Same author

Dual effects of nimesulide, a COX-2 inhibitor, in human platelets.

Life sciences·1998
Same author

Mucosal calcified nodule of the hard palate in an infant: case report and review of the literature.

Pediatric pathology & laboratory medicine : journal of the Society for Pediatric Pathology, affiliated with the International Paediatric Pathology Association·1997

Primary cardiac angiosarcomas are rare and often present with nonspecific symptoms. Early diagnosis can be challenging, even with thorough pathological examination, highlighting the need for broad differential diagnoses.

Area of Science:

  • Cardiovascular Pathology
  • Oncology
  • Diagnostic Imaging

Background:

  • Primary cardiac malignancy is exceptionally rare, with angiosarcomas being the most common type.
  • Diagnosis of cardiac angiosarcomas is frequently complicated by nonspecific clinical presentations.
  • Subtle or absent cardiac symptoms can mask the presence of cardiac tumors.

Observation:

  • Two cases of primary cardiac angiosarcomas with unusual presentations that evaded clinical diagnosis are detailed.
  • In one instance, thorough examination and specimen sampling were lacking, leading to a missed pathological diagnosis.
  • Cardiac symptoms may be absent in patients with primary cardiac angiosarcoma.

Findings:

  • Nonspecific clinical presentations can obscure the diagnosis of cardiac angiosarcomas.

Related Experiment Videos

  • Thorough pathological examination is crucial for accurate diagnosis.
  • Systemic symptoms can be the primary manifestation of cardiac angiosarcoma.

    • Implications:

    • Cardiac angiosarcoma should be considered in the differential diagnosis for patients presenting with unusual systemic symptoms, including multisystemic hemorrhagic phenomena or disseminated pulmonary lesions.
    • Subtle cardiac abnormalities alongside peripheral tumors warrant consideration of cardiac angiosarcoma.
    • Increased awareness and diagnostic vigilance are necessary for timely detection of rare cardiac tumors.