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Iron absorption from a natural mineral water (Spatone Iron-Plus)
M Worwood1, W D Evans, R J Villis
1Department of Haematology, University of Wales College of Medicine and University Hospital of Wales, Cardiff, UK.
Abstract:
Spatone Iron-Plus is a naturally occurring mineral water from Trefriw Wells Spa in Gwynedd, Wales, UK which contains approximately 0.3 mg of iron per ml as ferrous sulphate. The water has been taken as a tonic since Victorian times. Iron absorption from Spatone Iron-Plus was measured in a whole body counter after labelling the water with [59Fe] ferrous sulphate. Absorption studies were carried out in 13 subjects. Mean absorption for 10 ml of Spatone Iron-Plus taken on an empty stomach was 23 percent. Absorption was related to body iron stores as assessed by serum ferritin. In subjects with a serum ferritin concentration of <10 mu g/I, absorption was approximately 40 percent but was <10 percent in subjects with ferritin concentrations of approximately 200 mu g/I. This study indicates that Spatone Iron-Plus provides iron in a highly bio-available form.