Phosphazenes: high molecular weight reference compounds for field desorption mass spectrometry

Area of Science:

• Analytical Chemistry
• Mass Spectrometry

Background:

• Conventional reference materials have limitations in field desorption mass spectrometry due to poor ionization sensitivity and insufficient peak detection.
• There is a need for high molecular weight reference compounds suitable for electron impact or field ionization techniques.

Purpose of the Study:

• To introduce hexakis (multifluoroalkoxy)cyclotriphosphazenes as advanced reference materials for mass spectrometry.
• To evaluate their performance compared to existing standards.

Main Methods:

• Synthesis of hexakis (multifluoroalkoxy)cyclotriphosphazenes.
• Analysis using electron impact and field ionization mass spectrometry.
• Comparison of mass spectral characteristics with tris(perfluoroalkyl)-s-triazine standards.

Main Results:

• Hexakis (multifluoroalkoxy)cyclotriphosphazenes demonstrate greater volatility, simpler synthesis, and enhanced mass spectral characteristics.
• Phosphazene mixtures effectively cover a broad mass range in both ionization modes.
• These compounds address the inadequacy of conventional materials for high mass ion analysis.

Conclusions:

• Substituted phosphazenes are highly effective reference materials for field desorption mass spectrometry.
• They offer improved performance and expand measurement capabilities for high mass ions.
• These compounds represent a significant advancement in mass spectrometry calibration and analysis.