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Hypertension in the elderly

L Hansson1

  • 1Department of Geriatrics, University of Uppsala, Sweden.

Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension
|October 1, 1996
PubMed
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Treating elderly hypertension with calcium antagonists may reduce cardiovascular risks more effectively than traditional diuretics or beta-blockers. Ongoing studies are evaluating these novel therapies in older adults.

Area of Science:

  • Cardiology
  • Geriatrics
  • Pharmacology

Background:

  • Hypertension management in the elderly is crucial for reducing cardiovascular morbidity and mortality.
  • Traditional treatments often involve diuretics or beta-blockers.
  • Novel therapies like calcium antagonists may offer superior cardiovascular benefits in elderly populations.

Purpose of the Study:

  • To explore the potential advantages of calcium antagonists in treating hypertension among the elderly.
  • To review current research and data on calcium antagonist use in elderly hypertensives.

Main Methods:

  • Review of ongoing clinical trials, including the Swedish Trial in Old patients with hypertension (STOP-Hypertension)-2 and Systolic hypertension in Europe (Syst-Eur) studies.
  • Analysis of existing data on nicardipine, a dihydropyridine calcium antagonist, in elderly hypertensive patients.

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Main Results:

  • Calcium antagonists are being investigated as a primary therapy in significant clinical trials for elderly hypertension.
  • Nicardipine data provides a basis for understanding dihydropyridine efficacy in this demographic.

Conclusions:

  • Calcium antagonists represent a promising therapeutic avenue for elderly hypertension, potentially surpassing traditional treatments in cardiovascular risk reduction.
  • Further research and data analysis are essential to confirm the long-term benefits of calcium antagonists in this patient group.