Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Muscarinic mechanisms in nerve cells

D A Brown1, F C Abogadie, T G Allen

  • 1Department of Pharmacology, University College London, UK.

Life Sciences
|January 1, 1997
PubMed
Summary

This review covers receptor subtypes and signaling pathways that control neuronal ion channel activity. It highlights recent findings in sympathetic neurons, hippocampal cells, and basal forebrain neurons.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

GW170817: Observation of Gravitational Waves from a Binary Neutron Star Inspiral.

Physical review letters·2017
Same author

GW170814: A Three-Detector Observation of Gravitational Waves from a Binary Black Hole Coalescence.

Physical review letters·2017
Same author

Treatment with the TGF-b superfamily cytokine MIC-1/GDF15 reduces the adiposity and corrects the metabolic dysfunction of mice with diet-induced obesity.

International journal of obesity (2005)·2017
Same author

GW170104: Observation of a 50-Solar-Mass Binary Black Hole Coalescence at Redshift 0.2.

Physical review letters·2017
Same author

Macrophage inhibitory cytokine-1/growth differentiation factor-15 as a predictor of colonic neoplasia.

Alimentary pharmacology & therapeutics·2017
Same author

Upper Limits on the Stochastic Gravitational-Wave Background from Advanced LIGO's First Observing Run.

Physical review letters·2017

Area of Science:

  • Neuroscience
  • Cellular Biology
  • Molecular Biology

Background:

  • Neuronal function relies on the precise regulation of ionic currents.
  • Specific receptor subtypes and their associated transduction mechanisms play critical roles in modulating these currents.
  • Understanding these regulatory processes is key to deciphering neuronal communication and function.

Purpose of the Study:

  • To review the receptor subtypes and transduction mechanisms governing neuronal ionic currents.
  • To present recent observations on these mechanisms in specific neuronal populations.

Main Methods:

  • Literature review of existing research on neuronal ionic current regulation.
  • Synthesis of recent experimental findings from studies on sympathetic neurons, hippocampal cell membranes, and basal forebrain cells.

Related Experiment Videos

Main Results:

  • Identified diverse receptor subtypes involved in ionic current modulation.
  • Detailed various signal transduction pathways impacting neuronal excitability.
  • Presented novel observations from sympathetic, hippocampal, and basal forebrain neuronal studies.

Conclusions:

  • Receptor-mediated regulation of ionic currents is complex and cell-specific.
  • Transduction mechanisms are crucial for neuronal plasticity and function.
  • Further research is needed to fully elucidate these pathways in different neuronal systems.