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Evaluation of an aqueous injection of ketoprofen

A K Singhai1, S Jain, N K Jain

  • 1Department of Pharmaceutical Sciences, Dr. H. S. Gour University, Sagar (M.P.) India.

Die Pharmazie
|February 1, 1997
PubMed

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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.