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Thiamine supplementation mood and cognitive functioning

D Benton1, R Griffiths, J Haller

  • 1Department of Psychology, University of Wales Swansea, UK.

Psychopharmacology
|January 1, 1997
PubMed
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This study found that thiamine (vitamin B1) supplementation improved mood and reaction times in young women, even those with adequate thiamine levels. Memory was unaffected by the vitamin B1 intake.

Area of Science:

  • Nutritional Neuroscience
  • Human Physiology

Background:

  • Thiamine (vitamin B1) is essential for energy metabolism and neurological function.
  • Adequate thiamine status is crucial for optimal cognitive and psychomotor performance.

Purpose of the Study:

  • To investigate the effects of thiamine supplementation on mood, memory, and reaction times in young adult females.
  • To determine if benefits occur even in individuals with initially adequate thiamine levels.

Main Methods:

  • A double-blind, placebo-controlled study involving 120 young adult females over 2 months.
  • Participants received either 50 mg of thiamine daily or a placebo.
  • Mood, memory, and reaction times were assessed before and after the supplementation period.

Main Results:

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  • Improved thiamine status correlated with enhanced feelings of clarity, composure, and energy.
  • Thiamine supplementation led to significantly faster reaction times.
  • No significant effects on memory performance were observed.

Conclusions:

  • Thiamine supplementation can positively influence mood and psychomotor speed in young women.
  • These benefits were observed despite participants having adequate thiamine status at baseline.
  • Further research may explore the specific mechanisms underlying these effects.