Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cholangiocarcinoma: delayed CT contrast enhancement patterns

J M Lacomis1, R L Baron, J H Oliver

  • 1Department of Radiology, University of Pittsburgh Medical Center, PA 15213-2582, USA.

Radiology
|April 1, 1997
PubMed
Summary

Delayed contrast enhancement on CT scans is a typical feature of intrahepatic cholangiocarcinoma. This finding aids in the detection and characterization of these liver tumors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Regulatory T Cell Infusion Can Enhance Memory T Cell and Alloantibody Responses in Lymphodepleted Nonhuman Primate Heart Allograft Recipients.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2015
Same author

Isolation of live Borrelia burgdorferi sensu lato spirochaetes from patients with undefined disorders and symptoms not typical for Lyme borreliosis.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2015
Same author

Communication gaps associated with donor-derived infections.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2014
Same author

Cancers among US organ donors: a comparison of transplant and cancer registry diagnoses.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2014
Same author

Re-examination of the lymphocytotoxic crossmatch in liver transplantation: can C4d stains help in monitoring?

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2011
Same author

Donor-transmitted malignancies in organ transplantation: assessment of clinical risk.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2011

Area of Science:

  • Radiology
  • Oncology
  • Hepatology

Background:

  • Intrahepatic cholangiocarcinoma (ICC) is a primary liver cancer.
  • Accurate diagnosis and characterization are crucial for patient management.

Purpose of the Study:

  • To evaluate the utility of delayed post-equilibrium-phase contrast-enhanced computed tomography (CT) images for diagnosing ICC.
  • To determine if delayed enhancement patterns correlate with tumor characteristics.

Main Methods:

  • Retrospective review of 47 patients with pathologically proven ICC.
  • Analysis of unenhanced, dynamic contrast-enhanced, and delayed CT scans (6-36 minutes post-contrast).
  • Comparison of tumor enhancement patterns with surrounding liver parenchyma and histopathologic findings.

Related Experiment Videos

Main Results:

  • 74% of ICC tumors showed mild or marked hyperattenuating delayed contrast enhancement.
  • 18 tumors had homogeneous hyperattenuating enhancement on delayed images.
  • Delayed images were crucial for detecting ICC in some patients, and enhancement correlated with tumor fibrosis.

Conclusions:

  • Delayed tumoral contrast enhancement is a characteristic finding in ICC.
  • Delayed-phase CT imaging can improve the detection and characterization of intrahepatic cholangiocarcinoma.