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C-peptide does not alter carbohydrate metabolism in isolated mouse muscle
P N Shashkin1, Y Jiao, H Westerblad
1Division of Clinical Physiology, Department of Surgical Sciences, Karolinska Institute, Karolinska Hospital, Stockholm, Sweden.
The American Journal of Physiology
|February 1, 1997
Abstract:
The effects of C-peptide on carbohydrate metabolism in isolated mouse soleus muscle were studied. C-peptide, at concentrations up to 1,000 nM, had no effect on [14C]glucose incorporation into glycogen, glycogen synthase activity, or 2-deoxyglucose uptake. These data demonstrate that C-peptide has no direct effect on the measured parameters of carbohydrate metabolism in isolated mouse muscle.