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Updated: Jul 22, 2026

Staphylococcus aureus Growth using Human Hemoglobin as an Iron Source
Published on: February 7, 2013
Siderophore production by Staphylococcus aureus and identification of iron-regulated proteins
R J Courcol1, D Trivier, M C Bissinger
1Bacteriology Laboratory, A. Calmette Hospital, Lille, France.
Abstract:
Siderophore activity of Staphylococcus aureus was detected in an iron-restricted chemically defined medium. The molecular mass of this siderophore, called aureochelin, was 577 Da. Surface-associated proteins of 120, 88, 57, 35, and 33 kDa were mainly expressed under iron restriction conditions. Results showed a relationship between siderophore production and the existence of the 120- and 88-kDa proteins. Western blotting of surface-associated proteins revealed that these proteins were recognized both by patients sera and polyclonal rabbit serum.
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