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Related Experiment Videos

Infected abdominal aortic aneurysms. Experience with 14 consecutive cases

S Sriussadaporn1

  • 1Department of Surgery, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

International Surgery
|October 1, 1996
PubMed
Summary

In situ grafting for infected aortic aneurysms is safe with no or mild infection. Severe infections require alternative treatments, and long-term antibiotics are recommended.

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Area of Science:

  • Vascular Surgery
  • Infectious Diseases

Background:

  • Infected aortic aneurysms are life-threatening conditions requiring prompt and effective treatment.
  • Treatment options for infected aortic aneurysms are limited and associated with high morbidity and mortality.
  • Gram-negative enteric bacteria are common causative agents of aortic infections.

Purpose of the Study:

  • To evaluate the safety and efficacy of in situ grafting for infected aortic aneurysms.
  • To determine the impact of periaortic infection severity on treatment outcomes.
  • To assess the role of long-term antibiotic therapy in managing infected aortic aneurysms.

Main Methods:

  • Retrospective study of 14 patients with infected aortic aneurysms treated between 1990 and 1995.
  • Classification of periaortic infection severity into no, mild, and severe.

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  • Surgical interventions included in situ grafting and axillobifemoral bypass.
  • Microbiological analysis of aneurysmal sac or contents for bacterial cultures.

    • Main Results:

    • Eight patients with no or mild periaortic infection underwent in situ grafting, all survived with no subsequent graft infection.
    • Six patients with severe periaortic infection had poorer outcomes, with 5 out of 6 dying from sepsis or complications.
    • Gram-negative enteric bacteria were identified in all positive cultures.

    Conclusions:

    • In situ grafting is a safe and effective option for infected aortic aneurysms with no or mild periaortic infection, provided adequate debridement.
    • Severe periaortic infection is associated with significantly higher mortality, necessitating alternative surgical approaches.
    • Long-term antibiotic administration is recommended for all patients with infected aortic aneurysms.