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Antibiotic-induced iatrogenic hemobilia
V R Huilgol1, S L Markus, N B Vakil
1University of Wisconsin Medical School-Milwaukee Clinical Campus 53233, USA.
The American Journal of Gastroenterology
|April 1, 1997
Summary
Antibiotic-induced vitamin K deficiency can cause hemobilia, a rare condition involving gastrointestinal bleeding, abdominal pain, and jaundice. This case highlights a novel cause of hemobilia complicating acalculous cholecystitis.
Area of Science:
- Gastroenterology
- Hepatology
- Internal Medicine
Background:
- Hemobilia is classically defined by a triad of gastrointestinal bleeding, right upper quadrant abdominal pain, and jaundice.
- Common causes include liver trauma and iatrogenic complications from hepatobiliary interventions.
Observation:
- A patient presented with symptoms suggestive of hemobilia.
- The patient had recently undergone antibiotic treatment and had acalculous cholecystitis.
Findings:
- The hemobilia was attributed to antibiotic-induced vitamin K deficiency.
- This represents an uncommon etiology for hemobilia.
Implications:
- Highlights a rare but significant complication of antibiotic therapy.
- Broadens the differential diagnosis for hemobilia, especially in patients with acalculous cholecystitis.
- Underscores the importance of considering vitamin K status in patients with unexplained bleeding and hepatobiliary pathology.