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Follicular lymphomatoid papulosis
The American Journal of Dermatopathology
|April 1, 1997
Summary
A rare follicular variant of lymphomatoid papulosis (LyP) was observed in a Japanese woman. This case suggests follicular LyP is a histological pattern of LyP involving hair follicles.
Area of Science:
- Dermatopathology
- Oncology
- Histopathology
Background:
- Lymphomatoid papulosis (LyP) is a rare cutaneous T-cell lymphoproliferative disorder.
- Follicular LyP is an uncommon histological variant characterized by involvement of the follicular epithelium.
Observation:
- A 60-year-old Japanese woman presented with a 10-year history of recurrent cutaneous eruptions.
- Clinically, lesions appeared as reddish, centrally depressed, dome-shaped papules on the forearms.
- Histological examination revealed features consistent with follicular LyP, including atypical cells surrounding hyperplastic follicular epithelia.
Findings:
- The patient exhibited both follicular LyP and typical nonfollicular LyP papules.
- Histological findings met established criteria for LyP, with mixed cellular infiltrates and specific cell types.
Implications:
- The simultaneous occurrence of follicular and typical LyP supports the hypothesis that follicular LyP represents a specific histological pattern of LyP.
- This finding broadens the understanding of LyP's diverse clinical and histological presentations.