Related Experiment Video
Updated: Aug 5, 2026
06:40
Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies
Published on: January 11, 2019
Ulnar nerve palsy in Paget's disease
Clinical Orthopaedics and Related Research
|January 1, 1977
Summary
Paget's disease of bone can cause humerus enlargement, leading to ulnar nerve palsy. Surgical transposition of the ulnar nerve effectively treated this condition in a reported case.
Area of Science:
- Orthopedic Surgery
- Neurology
- Bone Diseases
Background:
- Paget's disease of bone is a chronic condition characterized by abnormal bone remodeling.
- Enlargement of the humerus, particularly the medial epicondyle, can occur in advanced Paget's disease.
- Ulnar nerve palsy is a condition affecting the ulnar nerve, often caused by compression or entrapment.
Observation:
- A 73-year-old female patient presented with enlargement of the distal right humerus due to Paget's disease.
- The patient developed symptoms of ulnar nerve palsy.
- This specific association between Paget's disease-induced humeral enlargement and ulnar nerve palsy appears to be previously unreported.
Findings:
- Surgical transposition of the ulnar nerve anterior to the elbow was performed.
- The patient experienced complete relief of ulnar nerve palsy symptoms following the procedure.
Implications:
- This case highlights a potential, previously unrecognized complication of Paget's disease of bone affecting the elbow.
- Anterior ulnar nerve transposition is an effective surgical treatment for ulnar nerve palsy secondary to humeral expansion in Paget's disease.
- Further research may be warranted to understand the prevalence and pathophysiology of this association.
Related Concept Videos
01:37Neural Regulation
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
01:15Bones of the Upper Limb: Ulna
The ulna and radius are parallel bones of the antebrachium or the forearm. The ulna lies medially and consists of a bony tip called the olecranon process at its proximal end. This hook-like projection articulates with the olecranon fossa of the humerus and forms the "hinged" ulnohumeral part of the elbow joint. This joint facilitates forearm extension and flexion while preventing its hyperextension. Similarly, the coronoid process, another bony projection on the proximal/anterior side of the...
01:23Peripheral Artery Disease V: Postoperative Nursing Management
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
01:22Diabetic Neuropathy
DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...
01:24Parkinson Disease ll: Pathophysiology
Parkinson disease (PD) is a progressive neurodegenerative disorder primarily affecting movement, with additional non-motor features. Its pathophysiology involves complex interactions among genetic susceptibility, environmental exposures, and cellular dysfunction, including dopaminergic neuron loss, protein aggregation, and mitochondrial impairment.Selective NeurodegenerationA key feature is the degeneration of dopaminergic neurons in the substantia nigra pars compacta, leading to reduced...