Related Experiment Videos
[Experimental autoimmune labyrinthitis: evaluation of various models in guinea pigs]
J R García-Berrocal1, J Vicente, B Arellano
1Servicio de ORL, Clínica Puerta de Hierro, Universidad Autónoma de Madrid.
Acta Otorrinolaringologica Espanola
|January 1, 1997
Abstract:
Evidence of hearing loss in humans with systemic autoimmune disease has suggested the possibility of isolated forms of deafness originated by a autoimmune mechanism. Several authors reject McCabe's (1) proposed clinical description based mainly on response to treatment and have attempted to develop an animal model of autoimmune deafness. A comparative analysis was made of several experimental models of sensorineural hearing loss in guinea pigs developed in our laboratory for the study of this problem.