[Reoperations in Crohn's disease]

In the span of 23 years (1973-1995) 242 patients with Crohn's disease were operated on at the Department of Surgery in Hradec Králové. From this total number there were 146 (60.3%) men and 96 (39.7%) women. Eight patients (3.3%) died, in 4 cases (1.6%) carcinoma in Crohn's disease was found. Reoperations for recurrences were performed in 76 patients (31.4%), in 46 (60.5%) of them only 1 operation, in 18 (23.7%) 2 reoperations and in 12 patients (15.8%) 3 or more surgical treatments were necessary. Within the time interval mentioned above 124 different operations were done. Authors point out some factors that may affect the Crohn's disease recurrences, their influence was assessed even in the clinical set. A higher risk of recurrences and reoperations were found in women, patients younger than than 20 years, people with a short history prior to primary operation, in distal parts of intestine (ileum, rectum) localizations, in multiple gut involvement, after improper surgical performance, in cases of aggressive forms of disease and from other reasons (medicamentous post-operative treatment, immunological factors etc.). (Tab. 11, Fig. 1, Ref. 22.)