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Primary fibromyalgia and allergy
1Department of Physical Medicine and Rehabilitation, Faculty of Medicine, University of Akdeniz, Antalya, Turkey.
Clinical Rheumatology
|January 1, 1997
Summary
Primary fibromyalgia (PF) patients frequently experience allergies and common symptoms like sleep disturbance. This study found a significant allergy background in PF patients compared to controls.
Area of Science:
- Rheumatology
- Immunology
- Allergology
Background:
- Primary fibromyalgia (PF) remains controversial regarding its disease status.
- Research is ongoing to understand PF's underlying mechanisms and associated conditions.
Purpose of the Study:
- To investigate the prevalence of common symptoms and allergy markers in primary fibromyalgia patients.
- To compare these findings with an age- and sex-matched control group.
Main Methods:
- 32 primary fibromyalgia patients and a control group were assessed.
- Evaluated symptoms included migraine, irritable bowel syndrome, sleep disturbance, and morning stiffness.
- Allergy assessment involved serum IgE levels and allergic skin tests.
Main Results:
- High prevalence of sleep disturbance (71.9%) and morning stiffness (68.8%) in PF patients, showing a positive correlation.
- PF patients exhibited a significantly higher allergy background compared to controls.
- While serum IgE levels were elevated in PF patients, the difference was not statistically significant.
- Allergic skin tests were positive in 10 out of 15 PF patients.
Conclusions:
- Primary fibromyalgia patients frequently present with specific symptoms and a notable allergy background.
- The findings suggest a potential link between allergy and primary fibromyalgia, warranting further investigation.