[Mucinous adenocarcinomas of the large intestine in Crohn disease]

In two patients with Crohn's disease of long duration after more than 17 and 12 years respectively a mucinous adenocarcinoma of the ascending colon and a perianal mucinous carcinoma deriving from the anal ducts developed. The possible pathogenetic connections between chronic inflammatory bowel disease and tumour origin are considered. In particular, both the histologically identifiable dysplasia of the mucosa and the fistulae originating in the anal ducts are discussed.