[The use of dot blot method for the estimation of IgG antibodies among persons vaccinated against influenza]

The level of IgG antibodies before and post influenza vaccination for 6 strains of influenza A virus (4 representative for pandemics and 2 vaccine strains) was tested by dot blot method. Examinations was performed with 4 age groups (20 persons each), selected on the base of strain which probably caused primary infection in given group. No differences in answer to particular influenza A virus strains consistent with "original antigenic sin" were observed. High sensitivity of dot blot method was confirmed.