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[Seroprevalence of B19 parvovirus infection in patients with acute polyarthritis]
E Campoy Reolid1, A Casanova Rituerto, J Rodríguez Moreno
1Servicio de Reumatología, Hospital de Bellvitge Príncipes de España, Barcelona.
Abstract:
Over a period of 29 months, from January 1991 to December 1994, all cases of acute polyarthritis seen at the Rheumatology Service in our Institution were studied to determine the seroprevalence of parvovirus B19 (B19) infection. The variables studied included: age and sex of patients, presence of fever and rash, Anti-B19 IgM and IgE serological determinations (ELISA, Mardix Lab.), follow-up time and final diagnosis. The study included 36 patients (22 women and 14 men, mean age 34 +/- 19 years). Thirteen and seven patients had fever and cutaneous rash, respectively. Anti-B19 IgM serology was positive in 4 patients; in 2 of them IgG seroconversion was confirmed. The mean follow-up time was 14 +/- 9 months. Final diagnoses included undifferentiated polyarthritis, rheumatoid arthritis, B19 polyarthritis, systemic lupus erythematosus, and miscellaneous in 19, 7, 4, 2, and 4 patients, respectively. Seroprevalence of B19 infection in acute polyarthritis in our area was 11%, approximately.
Insights
Parvovirus B19 (B19) infection was found in 11% of acute polyarthritis cases. This study investigated B19 seroprevalence in patients with joint inflammation, identifying key diagnostic markers.
Area of Science:
- Rheumatology
- Virology
- Immunology
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