[Agnogenic myeloid metaplasia with eosinophilia]

We report a patient with agnogenic myeloid metaplasia (AM) and pathological karyotype: 46 xy/45 xy, -4 der(7), del(14) (q 13), der(16), der(18). One year after the diagnosis of marked eosinophilia, fibrosis of cardiac valves and dermal infiltration of eosinophils were recorded. The course of the disease was long. The patient was alive seven years after the diagnosis. This is a myeloproliferative variant of hypereos-inophilic syndrome.