[Non-Hodgkin's lymphoma of the thyroid gland--2 case reports]

The authors present two female patients with Non-Hodgkin's lymphoma of the thyroid gland. The first had Non-Hodgkin's lymphoma, follicular, diffuse of centrocytic cells (FCC-intermediate grade risk), and the second had an immunoblastic Non-Hodgkin's lymphoma with large cells (high grade risk). After "staging" procedures, it was estimated that the first patient was in I EA and the second in II EB clinical stage. They were treated by surgical removal of involved tissue, combined chemotherapy and local radiotherapy. A complete remission was achieved in both patients without signs of recidivation for 8 months in one patient and 18 months in the second subject, after treatment. The elder patients more often manifest this type of lymphoma, especially if they already had chronic thyroiditis of Hashimoto's type. Using the combined, contemporary treatment, the overall five-years survival is about 56 +/- 7 percent.