[The pathogenic role of Helicobacter pylori]

The urease test and bacterioscopy of impression smears were used to detect Helicobacter pylori (HP) in biopsies from pyloric gastric mucosa of 77 (89.5%) of 86 chronic gastritis patients, of 27 (4%) from 32 duodenal ulcer patients, of 84 (84.0%) from 100 healthy male subjects aged 18-20. There was focal hyperemia in pyloric part of the stomach in 59 patients, leukocytic infiltration of mucous membrane was found histologically in 78 ones. Close correlation between complaints, endoscopic and histological shifts, HP incidence rate was not registered. Positive results in determination of HP antibodies by enzyme immunoassay (EIA) were obtained in 32 (45.7%) of healthy subjects. EIA findings and histological evidence on HP presence failed to coincide in 42 (92.9%) duodenal ulcer patients.