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Minimally Invasive Establishment of Murine Orthotopic Bladder Xenografts
Published on: February 11, 2014
[Implants in urology]
T Huschke1, D H Zermann, J Schubert
1Klinik und Poliklinik für Urologie, Friedrich-Schiller-Universität Jena.
Zeitschrift Fur Arztliche Fortbildung
|January 1, 1997
Summary
Urologic implants, including penile prostheses and artificial urinary sphincters, have advanced significantly. Research is ongoing to improve materials and address complications like infection, which often necessitates device removal.
Area of Science:
- Biomedical Engineering
- Urology
- Materials Science
Context:
- The use of implants in urology and other surgical fields has grown exponentially over the last 30 years.
- Genitourinary prostheses have evolved from simple testicular substitutes to complex devices like penile prostheses and artificial urinary sphincters.
- Current research investigates the host-implant interactions and material degradation of silicone-based urologic prostheses.
Purpose:
- To provide clinicians with an overview of complex urologic implants.
- To highlight current developments in neurological prostheses within urology.
- To discuss the challenges and complications associated with urologic implants.
Summary:
- Urologic implants, predominantly made of silicone, face challenges including local tissue reactions and material deterioration.
- Periprosthetic infection remains the most severe complication, often necessitating device removal.
- Advancements are being made in materials science and research into host responses to improve implant longevity and safety.
Impact:
- Enhanced understanding of urologic implant materials and their host interactions.
- Improved clinical management strategies for patients with urologic implants.
- Foundation for future developments in artificial bladder and ureteral materials.
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