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Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
Published on: October 16, 2013
Anaesthesia and emerging infectious diseases
1Centre for Infectious Diseases and Microbiology, Westmead Hospital, 2145, Australia.
Abstract:
New infectious diseases and microorganisms continue to be described. They may be blood- or arthropod-borne, or spread by the respiratory, sexual or faecal-oral route; in some cases, modes of transmission remain unknown or new ones have been described. Complex factors have contributed to the re-emergence of older pathogens in both developing and developed countries. Changes in medical and surgical practice have led to the frequent description of resistant gram-positive and negative bacteria, fungi and bacteria. Although many of the newly described agents may not be directly relevant to routine anaesthetic and intensive care practice, their impact on both patients and staff can be minimized by adherence to rational infection control guidelines, understanding of local disease and anti-microbial resistance patterns, sensible patient evaluation and access to expert advice. Given recent history, it can be expected that new microorganisms and clinical syndromes will continue to appear.
Insights
New infectious diseases and resistant pathogens are emerging globally. Adhering to infection control guidelines and understanding local resistance patterns are crucial for managing risks in healthcare settings.
Area of Science:
- Infectious Diseases
- Microbiology
- Public Health
Background:
- Emerging infectious diseases and microorganisms are continually being identified.
- Both novel and re-emerging pathogens pose global health challenges.
- Antimicrobial resistance in bacteria, fungi, and other microorganisms is a growing concern.
Purpose of the Study:
- To highlight the continuous emergence of new infectious agents.
- To discuss the factors contributing to pathogen re-emergence.
- To emphasize the importance of infection control and antimicrobial stewardship.
Main Methods:
- Literature review of emerging infectious diseases and antimicrobial resistance.
- Analysis of transmission routes and contributing factors.
- Discussion of implications for clinical practice and infection control.
Main Results:
- New infectious agents are identified through various transmission routes, some with unknown mechanisms.
- Resistant microorganisms are frequently described due to changes in medical practices.
- Established pathogens are re-emerging in both developed and developing countries.
Conclusions:
- Effective management of new and re-emerging infectious diseases requires adherence to infection control guidelines.
- Understanding local epidemiology and antimicrobial resistance patterns is essential.
- Proactive patient evaluation and access to expert advice are critical for minimizing impact.
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