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Preliminary X-ray crystallographic data for a myotoxin from Agkistrodon contortrix laticinctus (broad-banded
A C Treharne1, S P White, C L Ownby
1Laboratory of Crystallography, Oklahoma Medical Research Foundation, Oklahoma City 73104, USA.
Abstract:
A Type II phospholipase A2 myotoxin from Agkistrodon contortrix laticinctus was purified to homogeneity and crystallized. The protein had only myotoxic activity. X-ray diffraction quality crystals were obtained by the hanging drop vapour diffusion method from a crystallization solution containing 2.0 M ammonium sulphate. X-ray data were collected to a resolution of 2.3 A, and the crystals are fully characterized.