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Related Experiment Videos

Physical exercise after induced alkalosis (bicarbonate or tris-buffer)

W Kindermann, J Keul, G Huber

    European Journal of Applied Physiology and Occupational Physiology
    |October 31, 1977
    PubMed
    Summary

    Bicarbonate and Tris-buffer infusions did not improve 400m run performance in males despite increasing blood pH. This suggests that blood pH may not be the primary performance-limiting factor in maximal exercise.

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    Area of Science:

    • Exercise Physiology
    • Biochemistry

    Background:

    • Metabolic acidosis occurs during maximal exercise.
    • Buffering substances like bicarbonate are thought to mitigate acidosis and improve performance.

    Purpose of the Study:

    • To investigate the effect of bicarbonate and Tris-buffer infusions on maximal exercise performance.
    • To determine if enhanced buffering capacity influences performance in a 400m run.

    Main Methods:

    • 10 healthy males in their twenties participated.
    • Infusions of bicarbonate and Tris-buffer were administered.
    • Performance was assessed via 400m run time, maximal lactate concentration, and heart rate.

    Main Results:

    • No significant changes in run time, maximal lactate, or heart rate were observed.

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  • Post-exercise pH increased by approximately 0.1 unit.
  • Arterial pCO2 increased due to respiratory compensation.

    • Conclusions:

    • Enhanced buffering capacity did not improve maximal exercise performance.
    • The study questions the role of blood pH as a critical performance-limiting factor in brief, intense exercise.
    • No evidence for alterations in intracellular pH was found.