Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cyclins, cyclin-dependent kinases and differentiation

C Y Gao1, P S Zelenka

  • 1Laboratory of Molecular and Developmental Biology, National Eye Institute, NIH, Bethesda, MD 20892-2730, USA.

Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology
|April 1, 1997
PubMed
Summary

Cyclin-dependent kinases and cyclins regulate cell division but may also have roles in differentiated cells. This review explores their potential functions beyond cell cycle control.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Progress in the study of poor response to proprotein convertase subtilisin/kexin type 9 monoclonal antibodies].

Zhonghua xin xue guan bing za zhi·2026
Same author

[The relationship between variant angina pectoris syncope and coronary artery spastic targeted location, arrhythmia and coronary artery stenostic lesion].

Zhonghua xin xue guan bing za zhi·2025
Same author

[Application of modified percutaneous closure in the treatment of ventricular septal rupture after acute myocardial infarction].

Zhonghua xin xue guan bing za zhi·2024
Same author

[Correlation between coronary artery tortuosity and poor prognosis in patients with septal hypertrophic cardiomyopathy].

Zhonghua xin xue guan bing za zhi·2024
Same author

[Observation on the clinical outcomes of continued pregnancy following cesarean scar pregnancy in 55 women].

Zhonghua fu chan ke za zhi·2023
Same author

[Sacubitril/valsartan attenuates left ventricular remodeling and improve cardiac function by upregulating apelin/APJ pathway in rats with heart failure].

Zhonghua xin xue guan bing za zhi·2022

Area of Science:

  • Molecular Biology
  • Cell Biology
  • Biochemistry

Background:

  • Cyclin-dependent kinases (CDKs) and cyclins are key regulators of the cell cycle.
  • These proteins are also found in differentiated cells that are not actively dividing.

Purpose of the Study:

  • To review the known functions of cyclins and CDKs in differentiated, non-cycling cells.
  • To investigate potential roles of these proteins independent of cell cycle progression.

Main Methods:

  • Literature review of existing studies on cyclins and CDKs in differentiated cells.
  • Analysis of data to identify non-cell cycle-related functions.

Main Results:

  • Evidence suggests cyclins and CDKs are expressed in various differentiated cell types.

Related Experiment Videos

  • Emerging data points to functions beyond cell cycle regulation, such as gene transcription and cell differentiation.

    • Conclusions:

    • Cyclins and CDKs likely possess critical functions in differentiated cells unrelated to cell cycle control.
    • Further research is needed to fully elucidate these novel roles.