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Related Experiment Videos

Hepatic resection for hepatocellular carcinoma

T Nonami1, A Harada, T Kurokawa

  • 1Department of Surgery II, Nagoya University School of Medicine, Showa-ku, Japan.

American Journal of Surgery
|April 1, 1997
PubMed
Summary

pTNM staging accurately predicts survival after liver cancer surgery. Stage I/II patients had better outcomes than Stage III/IV, but further stratification is needed for precise prognosis. This aids treatment decisions.

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Topic: Incisional Hernia - "Easy case" as daily case: open vs lap, where the mesh, which fixation…in center midline cases.

Hernia : the journal of hernias and abdominal wall surgery·2015

Area of Science:

  • Hepatobiliary surgery
  • Surgical oncology
  • Gastroenterology

Background:

  • Hepatocellular carcinoma (HCC) is a major global health concern.
  • Hepatic resection is a primary curative treatment for HCC.
  • Accurate prognostic staging is crucial for patient management and outcome prediction.

Purpose of the Study:

  • To evaluate the prognostic significance of the pTNM staging system in patients undergoing hepatic resection for HCC.
  • To identify key factors influencing survival after HCC resection.

Main Methods:

  • Retrospective analysis of 262 patients who underwent hepatic resection for HCC.
  • Correlation of pTNM stages with survival rates.
  • Multivariate analysis to identify independent prognostic factors.

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Main Results:

  • pTNM stages showed a significant correlation with overall survival rates.
  • Stage I and II patients had significantly higher survival rates compared to Stage III and IV patients.
  • Tumor size (>2 cm), multiple tumors, positive surgical margins (<1 cm), and Child C classification were independent predictors of poor survival.

Conclusions:

  • pTNM staging is a valuable prognostic tool for HCC patients after hepatic resection.
  • Stratification by pTNM stage and Child classification is recommended for comparing surgical outcomes.
  • Further refinement of staging may improve prognostic accuracy for HCC.