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Intradermal triamcinolone treatment of psoriatic onychodystrophy

T R Bedi

    Dermatologica
    |January 1, 1977
    PubMed

    Insights

    Intradermal injections of triamcinolone acetonide show initial promise for psoriatic onychodystrophy but relapses are common. A side effect of hypopigmentation limits its widespread use for nail psoriasis.

    Area of Science:

    • Dermatology
    • Nail Diseases

    Background:

    • Psoriatic onychodystrophy is a challenging nail condition.
    • Current treatments for nail psoriasis have limitations.

    Purpose of the Study:

    • To evaluate the efficacy of intradermal triamcinolone acetonide injections for psoriatic onychodystrophy.
    • To assess the safety and side effects of this treatment.

    Main Methods:

    • Seven patients with psoriatic onychodystrophy received intradermal injections of triamcinolone acetonide.
    • Treatment response and adverse events were monitored.

    Main Results:

    • Initial therapeutic responses were positive in most patients.
    • Relapses of psoriatic onychodystrophy were frequently observed.
    • One patient experienced persistent periungual hypopigmentation.

    Conclusions:

    • Intradermal triamcinolone acetonide offers temporary relief for nail psoriasis.
    • The high rate of relapse and risk of hypopigmentation restrict its routine clinical application.
    • Further research into long-term efficacy and safety is warranted.

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