Spectrofluorimetric determination of diethazine and promethazine in pharmaceutical preparations

A simple, sensitive and accurate spectrofluorimetric method is described for the quantitative determination of diethazine and promethazine either in the pure form or in its pharmaceuticals. The method is based on the formation of red fluorescent product of these drugs with Au(III). A linear calibration graph is obtained over the range 0.05-100 p.p.m. of diethazine and promethazine.