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Hyperintense subcortical brain alterations in anorexia nervosa
K G Sieg1, M S Hidler, M A Graham
1Eating Disorders Unit, Willough at Naples, FL, USA.
Objective:
The results of past research have identified changes in brain structure in anorexia nervosa. We observed previously unreported MRI alterations in two cases of anorexia nervosa.
Method:
For both cases, we reviewed the clinical history, MRI scans and conducted a pertinent literature review.
Results:
The MRI brain scans of two patients with the diagnosis of anorexia nervosa revealed evidence of subcortical hyperintense changes on T2-weighted images.
Discussion:
No previous reports of these findings have been described in the literature on anorexia nervosa to date. Clinical and pathologic correlates associated with these brain observations in anorexia nervosa are discussed.