Related Experiment Videos
[Study by NMR of the modifications of brain lipid composition related to the tumor processes]
J C Debouzy1, F Fauvelle, N Fouilhe
1CRSSA, Service de Biophysique, La Tronche.
Annales Pharmaceutiques Francaises
|January 1, 1997
Abstract:
1H, 13C, 31P and 14N NMR spectroscopies were used to investigate the lipid composition of brain tumors (GL6 glioma) in rats, by comparison with controlateral hemispheres. Comparative indexes derived from NMR signal intensities were used to establish the statistical analysis. It was found that sterol metabolism and sphingolipid/glycerolipids ratio are significantly modified when a tumor is present.