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Calcium polysulfide overdose: a report of two cases
B Z Horowitz1, K Marquardt, E Swenson
1Division of Emergency Medicine and Clinical Toxicology, University of California, Davis Medical Center, Sacramento 95817, USA.
Journal of Toxicology. Clinical Toxicology
|January 1, 1997
Summary
Intentional ingestion of calcium polysulfide (lime-sulfur solution) can cause severe gastrointestinal injury, coma, and metabolic acidosis. This agricultural fungicide poses significant toxic risks when ingested.
Area of Science:
- Toxicology
- Gastroenterology
- Emergency Medicine
Background:
- Calcium polysulfide, a common agricultural fungicide, is readily available.
- Intentional ingestion cases are rare, with only two prior reports globally.
Observation:
- Two cases of intentional calcium polysulfide ingestion are detailed.
- Patients presented with altered mental status, severe metabolic acidosis, and coma.
- One patient experienced cardiac arrest and expired, with autopsy showing gastric necrosis.
Findings:
- Ingestion leads to direct caustic injury of the upper gastrointestinal tract.
- Systemic effects include metabolic acidosis, liver dysfunction, rhabdomyolysis, and renal failure.
- Esophageal and gastric mucosal burns can progress to esophageal strictures.
Implications:
- Calcium polysulfide ingestion is a serious medical emergency.
- Prompt recognition and aggressive supportive care are crucial for managing toxicity.
- Highlights the potential dangers of agricultural chemicals when misused.