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Cartilage viability with interpolated skin flaps: an experimental study

S S Park1, G J White, T A Cook

  • 1Department of Otolaryngology-Head and Neck Surgery, Oregon Health Sciences University, Portland, USA.

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
|April 1, 1997
PubMed
Summary

Determining the optimal timing for dividing a composite cartilage graft pedicle in nasal reconstruction remains unclear. This study found cartilage viability was consistently around 70% regardless of pedicle division time in rabbits.

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Area of Science:

  • Plastic Surgery
  • Regenerative Medicine
  • Biomaterials Science

Background:

  • Composite cartilage grafts are frequently used with midline forehead flaps for nasal defect repair.
  • Optimal timing for pedicle division to ensure graft viability is not established.

Purpose of the Study:

  • To investigate the impact of different pedicle division timings on the viability of composite cartilage grafts in nasal reconstruction using a rabbit model.

Main Methods:

  • A rabbit model was employed with five groups (n=5 each).
  • Skin flap pedicles were divided at 0 days, 4 days, 3 weeks, 6 weeks, and 10 weeks.
  • Cartilage graft viability and skin flap necrosis were assessed.

Main Results:

  • Early pedicle division (0 and 4 days) resulted in partial skin flap necrosis.

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  • Cartilage grafts demonstrated resilience, with viability around 70% across all division times.
  • No significant difference in cartilage viability was observed between the groups.

    • Conclusions:

    • The study suggests cartilage grafts tolerate ischemic periods better than anticipated.
    • Further research with larger grafts and refined flap critical period definition is needed.
    • Optimal pedicle division timing for composite cartilage grafts in this model could not be determined.