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Evaluation of an ion-selective electrolyte analyzer: Microlyte 6
V Markova1, I Sirakova, T Tsvetkova
1Department of Clinical Laboratory, University of Medicine, Plovdiv, Bulgaria.
Folia Medica
|January 1, 1997
Summary
The Microlyte 6 analyzer accurately measures key electrolytes including ionized calcium and magnesium. This ion-selective analyzer demonstrates reliable performance for clinical diagnostics.
Area of Science:
- Clinical Chemistry
- Biomedical Engineering
- Analytical Chemistry
Background:
- Electrolyte balance is critical for physiological function.
- Accurate measurement of ionized calcium and magnesium is clinically significant.
- Ion-selective analysis for ionized magnesium is a recent development.
Purpose of the Study:
- To evaluate the analytical reliability and operational characteristics of the Microlyte 6 ion-selective analyzer.
- To assess the simultaneous measurement of potassium, sodium, chloride, ionized calcium, ionized magnesium, and pH.
- To validate the analyzer's performance over a one-year period.
Main Methods:
- Evaluation of the Microlyte 6 ion-selective analyzer over approximately one year.
- Analysis of whole blood, serum, and plasma samples.
- Comparative analysis with the Kone Dynamic clinical chemistry analyzer.
Main Results:
- Coefficients of variation ranged from 0.49% to 4.42% for within-run and between-run analyses.
- Inaccuracy (d%) ranged from -4.23% to +4.06%.
- High correlation (0.9868-0.9970) observed for potassium, sodium, chloride, and ionized calcium compared to a reference analyzer.
Conclusions:
- The Microlyte 6 analyzer demonstrates reliable analytical performance for key electrolytes.
- Simultaneous measurement of ionized calcium and magnesium alongside other electrolytes is clinically valuable.
- The analyzer is operationally sound for routine clinical laboratory use.
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