Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Reflections on the years in interferon research

P M Pitha1

  • 1Department of Molecular Biology and Genetics, Johns Hopkins University, School of Medicine, Baltimore, MD 21231, USA.

Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research
|April 1, 1997
PubMed
Summary

Basic research in interferon and cytokine studies has driven field excitement and clinical applications. This review highlights 25 years of progress, emphasizing teamwork and collaboration in scientific discovery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unique contribution of IRF-5-Ikaros axis to the B-cell IgG2a response.

Genes and immunity·2012
Same author

Type I interferon: the ever unfolding story.

Current topics in microbiology and immunology·2007
Same author

The IRF family, revisited.

Biochimie·2007
Same author

ISG15 enhances the innate antiviral response by inhibition of IRF-3 degradation.

Cellular and molecular biology (Noisy-le-Grand, France)·2006
Same author

Cell defence against viral/bacterial infections: closer mechanism than anticipated?

Folia biologica·2004
Same author

Expression of human and macaque type I IFN transgenes interferes with HSV-1 replication at the transcriptional and translational levels: IFN-beta is more potent than IFN-alpha 2.

Virology·2002

Area of Science:

  • Immunology and Virology
  • Biomedical Research

Background:

  • The review reflects on 25 years of personal interferon research.
  • It emphasizes the crucial role of basic research in advancing the field.
  • The author acknowledges the Milstein family for supporting basic science.

Purpose of the Study:

  • To provide a personal overview of interferon research.
  • To highlight the impact of basic research on the field's progress and clinical applications.
  • To underscore the collaborative nature of modern scientific endeavors.

Main Methods:

  • This is a review based on personal recollections and experiences.
  • It synthesizes 25 years of research in the interferon field.
  • The narrative focuses on the evolution of understanding and application of interferons and cytokines.

Related Experiment Videos

Main Results:

  • Basic research has been fundamental to the excitement and progress in interferon studies.
  • Interferon research has provided a rational basis for novel clinical approaches.
  • Scientific progress in this field is a testament to team effort and collaboration.

Conclusions:

  • Basic research is essential for scientific innovation and clinical translation in immunology.
  • Interferon and cytokine research exemplifies the power of sustained scientific inquiry.
  • Collaboration and interaction are vital and rewarding aspects of a scientific career.