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Published on: August 14, 2017
The distribution of the vWF alleles and genotypes in the Palestinian population
H Khatib1, M Ezzughayyar, S Ayesh
1Department of Genetics, Silberman Life Sciences Institute, Hebrew University of Jerusalem, Israel.
Abstract:
Short tandem repeat (STR) loci amplified by PCR are known as a useful tool for individual identification and paternity testing. Direct PCR amplification from small amounts of whole blood is a rapid and convenient method for population screening for STR and VNTR markers. The allele frequencies of the vWF locus were determined for 127 unrelated Palestinians. Co-dominant segregation was observed in 20 mother/child pairs. Nine alleles were observed, with frequencies ranging from 0.004 to 0.327. Heterozygosity was 79%, and discrimination power was 0.927.
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